NSAIDS have antipyretic activity and can be used to treat fever.   Fever is caused by elevated levels of prostaglandin E2 , which alters the firing rate of neurons within the hypothalamus that control thermoregulation.   Antipyretics work by inhibiting the enzyme COX, which causes the general inhibition of prostanoid biosynthesis ( PGE2 ) within the hypothalamus .   PGE2 signals to the hypothalamus to increase the body's thermal set point.   Ibuprofen has been shown more effective as an antipyretic than paracetamol (acetaminophen).   Arachidonic acid is the precursor substrate for cyclooxygenase leading to the production of prostaglandins F, D & E.
getty-468152273-eggs-david- David Kiang Photography/getty images
Many doctors call eggs the "perfect food," given their high content of protein , vitamins A and B, and biotin. Eggs help offset inflammation because they contain the potent carotenoids zeaxanthin and lutein (both good for vision), as well as choline (good for brain and heart function). The first rule for enjoying these oval powerhouses is to always buy organic—and preferably "pasture-raised"—as these have higher levels of omega-3 fatty acids.
Upon endocytic PRR binding, actin - myosin cytoskeletal rearrangement adjacent to the plasma membrane occurs in a way that endocytoses the plasma membrane containing the PRR-PAMP complex, and the microbe. Phosphatidylinositol and Vps34 - Vps15 - Beclin1 signalling pathways have been implicated to traffic the endocytosed phagosome to intracellular lysosomes , where fusion of the phagosome and the lysosome produces a phagolysosome. The reactive oxygen species , superoxides and hypochlorite bleach within the phagolysosomes then kill microbes inside the phagocyte.